434.924.9333
Patient & Visitor Information

800.223.9173

Make an Appointment

434.924.9333

    

Cancer Center
Cancers We Treat

See All Cancers We Treat

Need a Second Opinion?

If you'd like to schedule an appointment for a second opinion, call 434.924.9333.

  

Need a Second Opinion?

If you'd like to schedule an appointment for a second opinion, call 434.924.9333.

Questions?

If you need to speak with someone about your appointment, call 434.924.9333.

  

Make an Appointment

If you'd like to make an appointment or get a second opinion, call 434.924.9333.

Google Search Cancer
Home > Cancers We Treat > Bone Cancer > Ewing's Sarcoma

Ewing's Sarcoma

Ewing's sarcoma is a cancerous bone tumor that may occur in any bone in the body. When it occurs in soft tissue, it is called extraosseous sarcoma. The most commonly affected areas include the pelvis, thigh, lower leg, upper arm, and chest wall.

A graphic depicting a front view of a male's leg and pelvis bones which are common Ewing's sarcoma sites
Leg and Pelvis Bones - Common Sarcoma Sites
Copyright © Nucleus Medical Media, Inc.

Causes

The causes of Ewing's sarcoma are not fully understood. Chromosomal rearrangement that alters the genes may be a factor.

Risk

Because the causes of the cancer are unknown, risk factors are also not fully understood. The following factors may increase your chance of developing Ewing's sarcoma:

  • Race: Caucasians
  • Age—Teenagers
  • Gender—Male

Symptoms

Symptoms include:

  • Pain, redness, and swelling surrounding the tumor
  • Fever
  • Weight loss and reduced appetite
  • Fatigue
  • Paralysis and incontinence in cases where the tumor is near the spinal cord
  • Numbness, tingling, and paralysis caused by compression of nerves by the tumor
  • Difficulty breathing if the tumor is in the chest wall

Diagnosis

Your doctor will ask about your symptoms and medical history. A physical exam will be done. You will be treated by a team of doctors which may include an oncologist who specializes in cancer, an orthopaedic surgeon who operates on bones, and a radiation oncologist who works with radiation to kill cancer cells.

Your bodily structures may need to be viewed. This can be done with:

  • X-rays
  • Bone scans
  • CT scan
  • MRI scan
  • PET/CT scan —to evaluate the metabolic activity of tissue

Your bodily fluids and tissues may need to be tested. This can be done with:

  • Blood tests
  • Biopsy
A graphic depicting a bone biopsy
Bone Biopsy
Copyright © Nucleus Medical Media, Inc.

Treatment

Treatment involves a combination of chemotherapy, surgery, and radiation. Typically, patients are first treated with chemotherapy for 8-12 weeks, followed by a CT or MRI scan to evaluate the tumor. Depending on the tumor size and location, either surgery or radiation follows. Chemotherapy then resumes for several months after surgery or radiation.

  • Chemotherapy
  • Surgery
  • Radiation Therapy
  • Future Therapy

Prevention

Ewing's sarcoma occurs for unknown reasons. There are currently no preventive measures to reduce the risk of developing the cancer.

 

Content was created using EBSCO’s Health Library. Edits to original content made by Rector and Visitors of the University of Virginia. This information is not a substitute for professional medical advice.