Precision Breast IORT
Precision Breast IORT | Clinical Trial
Precision Breast IORT (intraoperative radiation for breast cancer) offers image guided radiation treatment for women with early stage breast cancer. With this unique form of IORT, women receive concentrated radiation at the time of their lumpectomy, which combines multiple procedures into a single visit.
This is different from traditional early stage breast cancer treatment options that include mastectomy or lumpectomy and radiation that typically involves six weeks of daily treatments.
Precision Breast IORT is part of a clinical trial. Principal Investigator: Shayna Showalter, MD. IRB-HSR #18004 (Now Enrolling)
Do You Qualify for IORT?
UVA Cancer Center is currently enrolling participants in the Precision breast intraoperative radiation therapy (Precision Breast IORT) clinical trial. UVA Cancer Center is the only cancer center conducting this trial.
How Does IORT Work?
Precision Breast IORT at UVA Cancer Center uses CT imaging and high dose rate (HDR) brachytherapy to provide individualized radiation treatment for women at the time of their breast surgery. This procedure is being conducted as part of a clinical trial.
The clinical trial team includes breast surgical oncologists, radiation oncologists and brachytherapy physicists.
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A New Treatment for Breast Cancer
Precision Breast IORT is currently available at UVA as part of a clinical research trial, IRB#18004: “A Prospective Single-Arm Phase II Study to Investigate the Efficacy of Single-Fraction Intraoperative Radiation Treatment Using A Multi-Lumen Balloon Applicator and In-Room CT Imaging For the Treatment of Early-Stage Breast Cancer.”
A phase I safety and feasibility has been conducted at UVA using Precision Breast IORT. This trial confirmed that Precision Breast IORT is safe and feasible for the treatment of early stage breast cancer.
Benefits & Risks
Potential Benefits of Precision Breast IORT
- Better target volume coverage: CT imaging focuses the radiation dose to the lumpectomy bed, the area of the breast from which the tumor was removed.
- Normal tissue sparing: Customized treatment plan sculpts dose away from skin, ribs and heart.
- The ability to deliver a high dose of radiation to the lumpectomy bed: Precision Breast IORT delivers a higher prescription dose while maintaining the same maximum dose to breast tissue as compared to conventional IORT.
- Patient convenience: Individualized radiation delivered at the time of breast surgery.
Potential Risks of Precision Breast IORT
Risks of the procedure include:
- Hardness or changes in the way the breast feels during an exam