Partners in Discovery
Partners in Discovery
UVA Cancer Center is part of the Oncology Research Information Exchange Network (ORIEN), one of the largest cancer research networks in the country, and we use the Partners in Discovery for Total Cancer Care at UVA protocol (IRB HSR 18445) to share information and specimens with other researchers in the network. This program enables UVA to be part of larger efforts to find new ways to diagnose, treat and prevent cancer of all types.
How can patients become Partners in Discovery?
Every Patient is Unique
Just as every person is one-of-a-kind due to the unique combination of genes they inherit, cancer is unique as well. Cancers are usually classified by the organ in which they are first detected and how they look under a microscope, and this forms the basis for doctors to prescribe standard treatments.
However, we know that individual patients with “the same kind of cancer” do not always respond the same way to standard treatment. We now know that different tumors “of the same kind” have different types of gene mutations that cause them to behave and respond differently. This has led to the development of personalized medicine, where drugs are being developed and used to treat cancer on the basis of these molecular changes.
You can provide your own unique and special contribution to medical research in this field by allowing us to collect tissue and blood specimens from you, get information on your healthcare and share this with doctors and researchers across the country.
See Frequently Asked Questions to learn more about eligibility, enrollment process and how your information and samples will be shared.
Why is Sharing Good?
We believe that your generous donation of samples and information is best served if it can make the broadest impact in cancer research. Therefore, we are involved in several national research networks in which we share specimens and data, and we ask you to join us in these collaborations. We are part of the Oncology Research Information Exchange Network (ORIEN), one of the largest cancer research networks in the country, and we use the Partners in Discovery for Total Cancer Care at UVA protocol to share information and specimens with other researchers in the network.
How Partners in Discovery Can Help You
Through the ORIEN consortium, a large data set of medical information and tissue information is readily available to our physicians and researchers. Specimens can be requested from members across the network in an effort to quickly advance research. Collaborative projects, advancement of biomarker discovery and expansion of genomic analysis with academic partners and pharmaceutical companies are all possible through this innovative and exciting alliance.
The ORIEN Qlikview is a secure password-protected database that houses all of the clinical, tissue and molecular data from patients enrolled in the ORIEN program nationwide. Searches from this database can be used to find a cohort of patients for a potential research proposal, clinical trial or feasibility study. The program director has access to this database and can set up a query based on your research interests.
A research proposal can be submitted for internal review for scientific merit and resources requested. Upon approval, the research proposal will be submitted to the members of ORIEN for their option of participation.
Current Clinical Trials
We are leveraging the ORIEN network to expedite access to clinical trials.